Beware "herbal" remedies
Scores of traditional Chinese medicine stores in Britain's high streets are being investigated for selling illegal medicines, the BBC has learned.
Radio Five Live has discovered that 67 outlets selling Chinese medicines are under suspicion.
It is estimated that 6,000 stores across the country offer treatment for conditions ranging from eczema to the menopause.
But the industry, although growing in popularity, is largely unregulated.
At the Herb Garden store in Leigh on Sea, Essex, an undercover reporter from the Five Live Report was two weeks ago sold a herbal slimming pill and told it contained rhubarb and honeysuckle.
Tests showed it contained fenfluarmine - an illegal pharmaceutical considered to be so dangerous that it is banned in most countries worldwide, including the UK.
The owner of the store, Anna Yang, was prosecuted earlier this year for illegally selling the same drug.
But that's not all. The same BBC reporter was sold two other prescription-only drugs:
I am not familiar with either of these drugs, but a brief search showed that Danthron is carcinogenic, causing a large increase in adenomatous polyps of the colon in rats, and that it causes genetic damage in in vitro cell culture systems, with the money quote being: "Products containing Danthron as a laxative are no longer generally recognized as safe and effective and may not be marketed in the United States." Apparently, however, it is still used in Britain in the limited situation of severe constipation in terminally ill patients.The BBC reporter was also sold two other prescription-only drugs - Danthron - a specialist laxative which has cancer causing properties and is only recommended for use with terminally ill patients, and Sibutramine - prescribed in cases of extreme obesity.
If you think this doesn't have a human toll, think again:
Another doctor, Dr. Mark Thurz, agrees:Dr Karl Metcalfe, a consultant physician at Southend hospital said he has treated nine of Anna Yang's former patients but fears there may be more as some people may not have reported symptoms to their GPs.
"For a medically qualified person to be issuing these drugs would be reprehensible.
"For a non medically qualified person to be doing it is well very alarming and quite clearly criminal."
Dr Mark Thursz, a consultant physician at St Mary's Hospital in Paddington said he had seen a huge rise in the number of patients being referred to him with liver failure or hepatitis after taking Chinese herbal medicine.
He said: "Many people believe herbal remedies are safe, but they should be seen in the light as conventional remedies in that they can adverse reactions.
The lessons from this case, even though it happened in the U.K., are applicable to the U.S., because herbal medicines and supplements are just as poorly regulated here as they are in the U.K. You have very little assurance that the herbal remedies you purchase contain what they say they contain and in essence zero assurance that they do what the sellers claim they will do. Remember this as well: If a supplement, herbal remedy, or other treatment has any real effect on your body, it is acting as a drug, and all drugs have side effects. For all drugs, it is a question of risk versus benefit, whether the benefits of the drug outweigh its side effect profile and risks. In the case of fenfluramine, the benefits were outweighed by the risk of heart damage, which was why it was banned.
The distinction by alties between "natural" medicines and "artificial drugs" (those manufactured by drug companies) is artificial and designed to fool the unwary. Any "natural" or "herbal" remedy that has an objectively measurable therapeutic effect in your body is acting as a drug. Indeed, many of the drugs we use today for many purposes were initially discovered in nature, in plants or molds, or whatever. Penicillin, as most people know, came from a common mold. Digoxin is isolated from the foxglove plant (Digitalis purpurea). Taxol, now used to treat breast cancer and other malignancies, was isolated from the bark of the Pacific Yew tree. The difference is, when you use herbal remedies, unlike the case for drugs manufactured by pharmaceutical companies, you have very little assurance that you will actually be getting the correct amount of therapeutic components, that the amounts of those components won't vary considerably from lot to lot, or that the herbs haven't been treated with pesticides or spiked with something else. The whole reason "conventional" medicine moved away from using drugs directly in the form of plants or natural products and towards isolating the active components of those plants in purified form was to avoid these problems of variability and uncertainty in dosing. That is why, when you purchase, for example, digoxin, you can have assurance that, each time you buy it, a 0.125 mg pill will contain 0.125 mg of Digoxin within a very narrow range of variation and that it will not be adulterated with other components. You could munch on foxglove leaves, as was done before the active component was identified, but you'd be taking a chance. Given the narrow therapeutic window of digoxin, you'd have a high probability of either taking a dose too low to be therapeutic or of overdosing yourself.
The bottom line is that alties will raise a huge ruckus about problems with drugs like Vioxx being found after they have been approved by the FDA and on the market. Fair enough. Safety testing of drugs before approval has occasionally failed, but for the most part drugs that make it to market are safe and effective. Those that aren't are usually discovered fairly soon after release and use by a large population. Also, pharmaceutical companies pay a heavy price in terms of lawsuits if their drugs are found to be unsafe, an additional incentive to make sure that they are, in fact, safe. No such regulatory mechanism exists for herbal remedies and "supplements." This lack may not have been such a big deal a couple of decades ago, but, with more and more people using supplements and herbal remedies, this situation is no longer acceptable.